MonolixSuite in R
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getCACost

[Pkanalix] Get the value of minimized cost in CA

Get the value of the cost function minimized in CA, and additional criteria to compare models.

Usage

R
getCACost()

Value

A data frame with the values of total cost, -2LL, AIC and BIC computed during the last run.

Details

The detailed formulas for cost, -2LL, AIC and BIC are given in https://pkanalix.lixoft.com/ca-settings/.

  • Cost: weighted sum of squared residuals. Weights are specified in setCASettings. Additional weights are applied to balance the number of observations in each profile.

  • -2LL: Twice the negative log-likelihood based on the obtained cost.

  • AIC: Akaike Information Criteria calculated based on a penalization of -2LL by the number of optimized parameters.

  • BIC: Bayesian Information Criteria calculated based on a penalization of -2LL by the number of optimized parameters and the total number of data points.


See also

setCASettings getCASettings

Examples