Monolix

Documentation

• Introduction to Monolix

  • Why should you use Monolix?
  • The Monolix Workflow
  • Guide: From NONMEM to Monolix

• Data

  • Data overview
  • Loading a data set
  • Tagging a data set
  • Specifying observation types and regressor settings
  • Filtering a data set
  • + 4 more pages

• Structural model

  • Setting the structural model
  • Using or editing models from the libraries
  • Writing a model from scratch
  • Mapping between the data and the model
  • Model syntax: mlxtran language
  • + 3 more pages

• Statistical model

  • Observation model (residual error)
  • Individual model

• Tasks and results

  • Estimation tasks
  • Convergence assessment
  • Model building
  • Bootstrap
  • Output files
  • + 2 more pages

• Project comparison in Sycomore

  • Hierarchy
  • Comparison
  • Example

• Plots

  • General plot features
  • Data plots
  • Plots for structural model diagnosis
  • Plots for individual model diagnosis
  • Predictive checks
  • + 2 more pages

• Reporting

  • List of reporting keywords
  • List of plot settings
  • List of table settings

• Submissions and Reproducibility

  • Submission of Monolix analysis to regulatory agencies
  • Reproducibility of MonolixSuite results

• Running through command line

  • Parallelization over multiple nodes of a cluster