Introduction to Monolix

Monolix is the most advanced and user-friendly solution for non-linear mixed effects modeling (NLME) for pharmacometrics. It is based on the SAEM algorithm and provides robust, global convergence even for complex PK/PD models. Monolix is used for preclinical and clinical population PK/PD modeling and for Systems Pharmacology. Monolix enjoys a large user community. Monolix is widely used by academia, the pharmaceutical industry as well as the US regulatory agencies.

This documentation is for Monolix starting from 2018 version. For documentation of previous versions, please check Legacy Documentation.