setBioequivalenceSettings
[PKanalix] Set the value of one or several of the settings associated to the bioequivalence estimation
Set the value of one or several of the settings associated to the bioequivalence estimation. Associated settings are:
| "level" | (integer) | Level of the confidence interval |
| "bioequivalenceLimits" | (vector) | |
| Limit in which the confidence interval must be to conclude the bioequivalence is true | "computedBioequivalenceParameters" | |
| (data.frame) Parameters to consider for the bioequivalence analysis and if they should be log-transformed (true/false). This list must be a subset of the NCA setting "computedncaparamteters". | "linearModelFactors" | |
| (list) | The list can specify "id", "period", "formulation", "sequence" and "additional". The values are headers of the data set, except for reference where it must be one of the categories of the "formulation" categorical covariate. For "additional", a vector of headers can be given. | |
| "degreesFreedom" | (character) | t-test using the residuals degrees of freedom assuming equal variances ("residuals") or using the Welch-Satterthwaite degrees of freedom assuming unequal variances ("WelchSatterthwaite", default) |
Usage
R
setBioequivalenceSettings(...)Arguments
- ...
A collection of comma-separated pairs {settingName = settingValue}.
See also
Examples
R
if (FALSE) {
setBioequivalenceSettings(level = 90, bioequivalencelimits = c(85, 115)) # set the settings whose name has been passed in argument
setBioequivalenceSettings(computedbioequivalenceparameters = data.frame(parameters = c("Cmax", "Tmax"), logtransform = c(TRUE, FALSE)))
setBioequivalenceSettings(linearmodelfactors = list(id="SUBJ", period="OCC", formulation="FORM", reference="ref", sequence="SEQ", additional=c("Group","Phase")))
}